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Human Cell Atlas Will Be 'Google Maps' for Health Research

Scientists from around the world are making headway in compiling a Human Cell Atlas -- a deep dive into the myriad types of cells in the body and their disparate roles in health and disease.

The atlas is not yet complete, but 40 different scientific papers on cell research, published Nov. 20 in the journal Nature...

Doctors May Have New Weapon Against Flesh-Eating Bacteria

MONDAY, Aug. 5, 2024 (HeathDay News) -- A new antimicrobial compound can effectively clear “flesh-eating” bacterial infections in mice, a new study shows.

The compound could be the first in an entirely new class of antibiotics, which could prove invaluable in the fight against

  • Dennis Thompson HealthDay Reporter
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  • August 5, 2024
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    • FDA Approves New Drug to Treat Alzheimer's

    A new drug to treat Alzheimer's disease was approved by the U.S. Food and Drug Administration on Tuesday.

    In clinical trials, donanemab (Kisunla) modestly slowed the pace of thinking declines among patients in the early stages of the memory-robbing disease. But it also carried ...

    1 in 5 U.S. Cancer Patients Join in Medical Research

    More patients these days are taking part in cancer research, a new study finds.

    At least one in five people with cancer (22%) participate in some form of clinical research, when all types of cancer studies are considered, researchers found.

    Moreover, enrollment in cancer treatment trials wa...

    Researchers Find New Way to Curb Asthma Attacks

    A protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.

    The naturally occurring protein, called Piezo1, prevents a type of immune cell called type 2 innate lymphoid cells (ILC2s) from becoming hyperactivated by allergens.

    An expe...

    Biden to Sign Order Expanding Health Research in Women

    President Joe Biden plans to sign an executive order on Monday that will broaden the scope of medical research in women.

    The order "will direct the most comprehensive set of executive actions ever taken to expand and improve research on women's health," the White House said in a

  • Robin Foster HealthDay Reporter
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  • March 18, 2024
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    • Politics Hasn't Shaken Most Americans' Faith in Science: Study

    The Trump administration's attacks on scientists didn't shake Americans' confidence in science, a new analysis shows.

    "The proportion of Americans with a low level of trust in scientific expertise rose from 3% in 2016 to 13% in 2020," said lead author Jon Miller, a research scientist emeritus at the Center for Political Studies at the ...

    Jill Biden Announces $100 Million for Research on Women's Health

    First Lady Jill Biden on Wednesday announced $100 million in federal funding to fuel research into women's health.

    "We will build a health care system that puts women and their lived experiences at its center,"Biden said in a White House

  • Robin Foster HealthDay Reporter
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  • February 22, 2024
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    • Scientists Discover New Way to Fight Estrogen-Fueled Breast Cancer

    Everyone's heard of fighting fire with fire.

    Now that tactic is coming to breast cancer treatment.

    Researchers think they've figured out a better way to fight breast cancer fueled by the female hormone estrogen"by employing mechanisms used by the male hormone androgen.

    An experimental drug called enobosarm stimulates the androgen receptor on cancer cells, which functions as a ...

    Dana Farber Cancer Center to Retract or Fix Dozens of Studies

    The prestigious Dana Farber Cancer Institute in Boston will retract six studies and correct 31 more as part of an ongoing investigation into claims of data manipulation.

    The action follows allegations that a British molecular biologist posted in a blog earlier this month suggesting researchers...

    Human 'Brain Cell Atlas' Brings New Insight Into Brain Health, Illness

    After a massive five-year effort, researchers have unveiled an "atlas"that gives an unprecedented look at the intricacies of the human brain.

    The atlas, which will be available to researchers everywhere, can be seen as similar to the atlases we all know: a book of maps.

    But this one catalogues human brain c...

    Experimental Drug Could Rein in Epilepsy Seizures

    For people with tough-to-treat epilepsy, seizures can be both frightening and dangerous, but a new experimental pill may bring significant relief to over one-third of them.

    Dubbed XEN1101, the new drug reduced the frequency of seizures by more than 50%, or even eliminated them, in some patients with focal epilepsy who did not respond to an average of six other drugs.

    "I am predictin...

    Stem Cell Therapy Could Be Breakthrough Against Type 1 Diabetes

    People with type 1 diabetes lack functional islet cells in their pancreas to produce the hormone insulin and must take daily insulin via injections or a continuous pump to compensate.

    But if new research pans out, some folks with type 1 diabetes may no longer need ...

    Nobel Prize for Medicine Awarded to COVID Vaccine Pioneers

    This year's Nobel Prize for physiology or medicine has been awarded to two scientists who laid the groundwork years ago for the mRNA research that made COVID-19 vaccines possible.

    Dr. Katalin Karikó, the 13th woman to ever receive the honor, and

  • Cara Murez HealthDay Reporter
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  • October 2, 2023
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    • FDA Panel Says No to Experimental ALS Drug

    An advisory panel to the U.S. Food and Drug Administration on Wednesday voted resoundingly against recommending a stem cell-based experimental treatment for ALS.

    Although the FDA isn't bound by the votes of its advisory panels, agency scientists have already penned a scathing review of the drug, called NuOwn.

    Th...

    Normal Body Temperature Varies Between People

    You might think you know what a normal body temperature is, but there is no such thing.

    Analyzing the age-old belief that 98.6 Fahrenheit is normal human temperature, scientists at Stanford Medicine found that your temperature is personal.

    It also depends on age, sex, height and weight, and changes throughout the day.

    "Most people, including many doctors, still think that ever...

    U.S. Wastewater Tests Spot Highly Mutated Variant of COVID-19

    Public health officials have detected the new BA.2.86 variant of COVID-19 in U.S. wastewater, giving rise to concerns about the highly mutated variant in the United States.

    The U.S. Centers for Disease Control and Prevention announced the detection on Wednesday. ...

    Gene Study Reveals Brain's Complex Organization

    The brain is a complex organ, and a new study -- believed to be the largest ever on the brain's genetics -- identifies more than 4,000 genetic variants linked to brain structure.

    The research, involving some 36,000 brain scans, was led by a team at the University of Cambridge in England.

    Brains are quite varied in terms of overall volume, how the brain is folded and how thick the fo...

    Using Only 'Brain Recordings' From Patients, Scientists Reconstruct a Pink Floyd Song

    The famous Pink Floyd lyrics emerge from sound that is muddy, yet musical:

    "All in all, it was just a brick in the wall."

    But this particular recording didn't come from the 1979 album "The Wall," or from a Pink Floyd concert.

    Instead, researchers created it from the reconstituted brainwaves of people listening to the song "Another Brick in the Wall, Part 1."

    This is...

    New Lawsuit Filed by Family of Henrietta Lacks Over Unauthorized Use of Her Cells

    The family of Henrietta Lacks has filed another in a series of planned lawsuits over the use of Lacks' cells without her knowledge or consent.

    Known as the HeLa cell line, it has changed modern medicine because of the cells' unusual ability to survive in laboratories, making it possible for researchers to repro...

    Biotech Company Settles With Family of Henrietta Lacks, Whose Cells Revolutionized Medicine

    Cervical cells from Henrietta Lacks, a cancer patient who died more than 70 years ago, are a cornerstone of modern medicine, but her family has never been compensated for the cells taken without her knowledge.

    Until now.

    Thermo Fisher Scientific of Waltham, Mass., has settled a lawsuit filed in 2021 by the...

    New Clues to Treating a Disease That Prevents Children From Swallowing, Eating

    Children who have a chronic immune system disease that can prevent them from eating may eventually have a new treatment, decades after the condition was first identified.

    "Parents and doctors may not be aware of this, but this is a very prominent and serious disease in the pediatric population, and it is increasing in number because it is directly related to food allergens, which are also...

    B 7/12 -- New Bionic Hand Implant Allows Control of All Fingers

    A multinational team of engineers and surgeons has developed a bionic hand with a high level of function in every finger -- a significant advance for amputees.

    The team, from the United States, Sweden, Australia and Italy, developed a way to reconfigure what remains of a patient's limb. Then, they integrated sensors and a skeletal implant to connect with a prosthesis both electrically an...

    Scientists Develop 'All Species' COVID Test

    Researchers can now detect the COVID-19 virus in any animal using a new all-species test.

    It's an advance that they say will help track COVID-19 variants in wild and domesticated animals.

    "Highly sensitive and specific diagnostic reagents and assays are urgently needed for rapid detection and implementation of strategies for prevention and control of the infection in animals,"the re...

    Scientists Use Stem Cells to Replicate Early Human Embryo

    Scientists hope to learn more about the earliest stages of human development using models of embryos created from stem cells.

    The models, from University of Cambridge scientists, could ultimately shed light on why and how pregnancies fail, as well as on genetic disorders.

    The models are three-dimensional and created from stem cells, not egg and sperm, so they cannot grow into babies...

    First Synthetic Human Embryo Models Created in Lab

    Scientists say they have created the first synthetic human embryo models, not actual human embryos but models meant to simulate and better understand early human development.

    These embryo-like structures were created from single human embryonic stem cells, without eggs and sperm, by scientists in the United States and United Kingdom, CNN reported.

  • Cara Murez HealthDay Reporter
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  • June 15, 2023
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    • New Clues to Why Some People Suppress HIV Without Drugs

    Some HIV patients are naturally able to keep the virus fully in check without any medicinal help, a phenomenon that has intrigued scientists for decades.

    New research appears to identify at least one reason why: an abnormally powerful version of an infection-fighting white blood cell called CD8+ T cell.

    CD8+ T cell's are a type of T cell, a normal feature in everyone's immune s...

    Science Reveals Key Driver of Alzheimer's, and How Newly Approved Drug May Fight It

    Researchers have isolated for the first time a free-floating form of amyloid beta that appears to be a key driver of Alzheimer's disease.

    Further, they argue that a newly approved Alzheimer's drug -- lecanemab (Leqembi) -- directly targets these small, complex chains of amyloid beta (A-beta) called fibrils. The U.S. Food and Drug Administration approved lecanemab in January.

    The A-b...

    A More Diverse Human Genome: The 'Pangenome'

    Last year, gene researchers made news by announcing the completion of the first complete sequence of the human genome.

    That effort has now been expanded, with researchers using that success as a springboard to create a comprehensive and sophisticated collection of genome sequences that more accurately captures human diversity.

    The new "pangenome"includes the genome sequences of 47 d...

    International Group of Health Experts Raise Alarm About Dangers of AI

    Artificial intelligence (AI) research and development should stop until its use and technology are properly regulated, an international group of doctors and public health experts said.

    Certain types of AI pose an "existential threat to humanity,"the experts wrote in the May 9 issue of the journal

  • Cara Murez HealthDay Reporter
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  • May 10, 2023
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    • Shortage of Research Monkeys Threatens US Readiness for Health Emergencies: Panel

    The United States needs to address a shortage of research monkeys by expanding breeding programs while also developing alternatives to monkey testing, an expert panel said in a report released Thursday.

    The National Academies of Sciences, Engine...

    Ultrasound Breaches Blood-Brain Barrier, Helping Drugs Fight Tumors

    Brain cancers are notoriously difficult to treat because most chemotherapy drugs can't breach the blood-brain barrier, a microscopic layer of cells that protect the brain from toxins.

    But researchers now say they can temporarily open that barrier and get more chemo to brain tumors, using an experimental ultrasound device.

    The technology led to a four- to sixfold increase in chemo dr...

    New 'E-Tattoo' Is Worn on Chest to Track Your Heart Health

    Could an electronic chest "tattoo"-- wireless, lightweight and razor-thin -- upend heart monitoring and lower the odds of heart disease for folks who are at high-risk?

    Just possibly.

    The clear patch in question is not quite 4 by 5 inches in size, weighs less than an ounce, and is powered by a battery no bigger than a penny and just like a temporary tattoo sticker, it's designed to ...

    One-Time Endoscopic Treatment Might Replace Insulin for People With Type 2 Diabetes

    Could a one-hour procedure that involves zapping a part of the intestines mean no more insulin for millions of folks with type 2 diabetes?

    Maybe, according to a small study scheduled for presentation next week at the Digestive Disease Week meeting in Chicago.

    The new minimally invasive procedure used controlled electrical pulses to change the lining of the first part of the small i...

    Lack of Women Researchers Could Mean Fewer Female Study Participants

    When exercise studies are led by men, female participants are often in short supply.

    While this underrepresentation of female research subjects has been documented in everything from clinical trials to cell cultures, a new study links researchers' gender and women's participation.

    "Our findings provide direct evidence of the link between gender of authors and gender of research part...

    Scientists Get Closer to a 'Universal' Flu Vaccine

    Researchers are reporting progress on the path to a "universal" flu vaccine -- one that would battle all strains of the virus and give the world a weapon against future flu pandemics.

    In an early clinical trial, U.S. government scientists found that their experimental flu vaccine was able to coax recipients' immune systems to produce "cross-reactive" antibodies. That is, they made antibod...

    Blood-Based 'Liquid Biopsy' Might Spot Early-Stage Cancers

    An experimental blood test may be able to catch a dozen different types of cancer with a high degree of accuracy -- including some that are particularly tricky to detect, a preliminary study suggests.

    Researchers found that the blood test was usually on the money in detecting "signals" from 12 cancers. Importantly, the test was highly accurate in picking up early-stage cancer -- which is ...

    Mouse Study Points to New Way to Shrink Pancreatic Tumors

    New research in mice shows promise for a potential therapy for pancreatic cancer, which can be aggressive and hard to treat.

    Researchers from Houston Methodist tested a device that, while smaller than a grain of rice, could deliver immunotherapy directly into a pancreatic tum...

    US Sets Up $300 Million Database for Alzheimer's Research

    A new national Alzheimer's disease and dementia database could be a game changer for research on the memory-robbing condition that now affects more than 6 million Americans.

    Planning has begun at the National Institute on Aging (NIA) to fund the data platform. A $300 million grant for the six-ye...

    Monthly Injections Might Lower Bleeding in People With Hemophilia

    An experimental injectable drug appears effective in reducing bleeds in patients with hemophilia A and B, according to a pair of new clinical trials.

    Two-thirds of people with treatment-resistant hemophilia who were treated with the drug fitusiran had no bleeds at all after nine months, versus just 5% of people treated with drugs that enhance clotting, according to a trial published onlin...

    Bile Duct Cancer: Awareness, Funding Needed to Fight This Silent Killer

    Lawyer, entrepreneur and avid athlete Mark Clements participated in the 2005 St. George Marathon in Utah, but ongoing stomach pains made finishing the event a struggle.

    "He was having some stomach pain,"recalled his sister Stacie Lindsey. "My dad had had ulcers, and so he thought that he had ulcers."

    After finishing the marathon, Clements, then 38, went straight in to see his doctor...

    Cell Injections Show Promise Against Chronic Back Pain

    An injection that relieves low back pain by helping damaged spinal discs regenerate appears to have sustained benefits, new clinical trial data show.

    Most patients who received an injection of VIA Disc received back pain relief that lasted at least three years, said lead researcher Dr. D...

    Scientists Grow Electrodes in Living Tissue

    Swedish scientists say they have grown electrodes in living tissue, paving the way for formation of fully integrated electronic circuits in living organisms.

    The development, which blurs the lines between biology and technology, could one day lead to therapies for neurological disorders.

    "For several decades, we have tried to create electronics that mimic biology. Now we let biology...

    New Injected Drug May Prevent Severe COVID

    A single injection of an experimental biologic drug may cut in half your risk of hospitalization from COVID-19 infection, new clinical trial results show.

    Pegylated lambda interferon (PEG-lambda) proved effective against all COVID-19 variants encountered in this international study, including Omicron, according to findings reported Feb. 9 in the

  • Dennis Thompson HealthDay Reporter
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  • February 9, 2023
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    • Artificial Pancreas Device May Help Folks With Type 2 Diabetes

    An artificial pancreas has long been considered the holy grail for people with type 1 diabetes, and new research suggests a more convenient version of this technology may help the millions of people living with type 2 diabetes.

    Type 2 is the more common form of diabetes, and is clos...

    'Cellular Atlas' Could Be Step Against Endometriosis

    Few good treatment options exist for the millions of women dealing with the intense pain caused by endometriosis, but researchers say a new "cellular atlas" could help.

    A team at Cedars-Sinai Medical Center in Los Angeles has developed a detailed molecular profile of endometriosis using data from 400,000 patient cells.

    "Endometriosis has been an understudied disease in part becaus...

    Artificial Penis Tissue Restores Function in Pig Study

    A new study on pigs shows promise for repairing penile injuries in humans.

    Scientists in China developed a synthetic tissue that reportedly repairs injuries and restores normal erectile function in pigs. This artificial tunica albuginea (ATA) mimics a fibrous sheath of tissue that is necessary to maintain erections.

    "We noticed that this is an area that has received little attention...

    Move to Electric Cars Will Save Lives Plus Billions in Health Care Costs

    As the United States moves towards a world in which electric vehicles (EVs) have fully replaced fossil fuel-driven engines, can Americans look forward to reliably cleaner air and better health?

    Absolutely, a new study predicts.

    By 2050, researchers say, th...

    Twins Study Shows Exercise Altering How Genes Behave

    One might expect identical twins to have the same health outcomes.

    But it's not just genetics that makes a notable difference in their weight and in how their genes behave, according to a new study. Exercise can alter genetic markers of metabolic disease -- any of the diseases or disorders that disrupt norma...

    Scientists May Be Closer to Effective HIV Vaccine

    It's thought that for an HIV vaccine to be widely effective, it will have to spur the body to make special antibodies that can neutralize a broad range of HIV strains. Now scientists say they have taken an essential step in that direction.

    In an early study, researchers found that an experimental HIV va...